Personalization of Cardiac Motion and Contractility from Times Series of Images

Personalization is a key aspect of biophysical models in order to impact clinical practice. In this paper, we propose a personalization method of electromechanical models of the heart from cine MR images based on a variational method. After estimation of electrophysiological parameters, the cardiac motion is estimated based on a proactive electromechanical model. Then cardiac contractilities on two or three regions are estimated by minimizing the discrepancy between measured and simulation motion. Evaluation of the method on three patients with infarcted or dilated myocardium is provided.